1cP-MiPLA 225mcg Blotters

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1-Cyclopropionyl-N-methyl-N-isopropyllysergamide (also known commonly as 1cP-MiPLA) is a novel psychedelic substance of the lysergamide class. 1cP-MiPLA is closely related to MiPLA, for which it is suspected to be a prodrug. 1cP-MiPLA is a novel research chemical that seems to have appeared first in 2020 or 2021, allegedly first synthesized by either Skyler Ulrich or a chemist/group under the name of Gerstmann, alongside other novel lysergamides like 1cP-AL-LAD on various research chemical markets. User reports describe the effects of 1cP-MiPLA as similar to those of MiPLA. Some anecdotal reports state that there could be a notable, if even slight, difference between the two, although this does not indicate that it isn't a true prodrug for MiPLA. Many effects seem to be identical or nearly identical.

Chemistry

1cP-MiPLA, or 1-Cyclopropionyl-N-methyl-N-isopropyllysergamide, is a semisynthetic alkaloid of the lysergamide family. 1cP-MiPLA is a structural analog of lysergic acid, with an N-methyl-N-isopropylamide functional group bound to RN of the chemical structure. 1cP-MiPLA's chemical structure contains a bicyclic hexahydroindole fused to a bicyclic quinoline group (nor-lysergic acid). It is substituted at R1 with a cyclopropionyl substituent. At carbon 8 of the quinoline, a N,N-diethyl carboxamide is bound. 1cP-MiPLA is a chiral compound with two stereocenters at R5 and R8. 1cP-MiPLA, also called (+)-D-1cP-MiPLA, has an absolute configuration of (5R, 8R). The three other stereoisomers of 1cP-MiPLA presumably do not have psychoactive properties.

Pharmacology

1cP-MiPLA likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from 1cP-MiPLA's efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain an object of scientific elucidation. 1cP-MiPLA is also suspected to be a prodrug for MiPLA, given its 1-Cyclopropionyl substitution. This can be compared with 1cP-LSD, which is also likely a prodrug for LSD. However, there is not enough data, anecdotes, or guarantees that this will be the exact same property of 1cP-MiPLA. 1cP-MiPLA also shares many common traits with its parent compound LSD; in humans, it appears to be roughly equal (or less) in potency as well as similar in mechanism, although the progression and duration of effects are compressed (while remaining qualitatively less intense and more manageable - perhaps due to being catabolized more readily). It is also notably less potent.

Chemical Nomenclature

• Common names: 1cP-MiPLA
• Substitutive name: 1-Cyclopropionyl-N-methyl-N-isopropyllysergamide
• Systematic name: (6aR,9R)1-Cyclopropionyl-N-methyl-N-isopropyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo-[4,3-fg]quinoline-9-carboxamide

Class Membership

• Psychoactive class: Psychedelic
• Chemical class: Lysergamide

Dosage

• Threshold: 50 µg
• Light: 100 - 150 µg
• Common: 150 - 200 µg
• Strong: 200 - 250 µg
• Heavy: 300 µg +

Duration

• Total: 4 - 6 hours
• Onset: 20 - 40 minutes
• Come up: 45 - 90 minutes
• Peak: 1 - 2 hours
• Offset: 1 - 2 hours

1cP-MiPLA 225mcg Blotters is for research use only and not intended for human consumption!

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1cP-MiPLA 225mcg Blotters stock last updated at: April 2025