2C-EF 10mg Pellets

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5-dimethoxy-4-(2-fluoroethyl)phenethylamine (also known as 2C-EF) is a lesser-known psychedelic substance of the phenethylamine class. It is a member of the 2C-x family of psychedelic phenethylamines, which are closely related to the classical psychedelic mescaline. Like other psychedelics, it is thought to produce its effects by binding to serotonin receptors in the brain, although the precise mechanism is poorly understood.

Discovery

2C-EF was first mentioned by Alexander Shulgin in his book PiHKAL ("Phenethylamines I Have Known and Loved") and later referenced with a dosage range of 6 to 12mg and a duration of 12 hours.

Subjective Effects

Subjective effects include open and closed-eye visuals, time distortion, enhanced introspection, ego loss, and euphoria. User reports characterize 2C-EF, like 2C-E, as a highly unpredictable, dose-sensitive psychedelic capable of producing strong visual distortions. Many reports indicate that the safe use of this substance may be overly difficult for those who are not already experienced with hallucinogens.

History and Culture

2C-EF was first imagined by Alexander Shulgin, who documented his findings in the 1991 book PiHKAL ("Phenethylamines I Have Known and Loved"). As he states in the #63 DOEF chapter, "It would be every bit as much a treasure and ally as is 2C-B or 2C-I. In fact, I am sure enough about this prediction that I am willing to name the stuff 2C-EF."

Chemistry

2C-EF or 2,5-dimethoxy-4-(2-fluoroethyl)phenethylamine is a phenethylamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. 2C-EF contains methoxy functional groups (CH3O-) attached to carbons R2 and R5, and an ethyl chain bound to carbon R4 of the phenyl ring with a hydrogen replaced by fluorine on the last carbon of the ethyl group. 2C-EF belongs to the 2C family of phenethylamines, which contain methoxy groups on the 2 and 5 positions of the benzene ring.

Pharmacology

2C-EF's psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist.

2C-EF 10mg Pellets is for research use only and not intended for human consumption!

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2C-EF 10mg Pellets stock last updated at: April 2025