Deschloroetizolam 5mg Pellets

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Deschloroetizolam is a short-acting psychoactive substance belonging to the thienodiazepine class, recognized for its diverse range of effects, including depressant, anxiolytic, sedative, hypnotic, muscle relaxant, anticonvulsant, and amnesic properties. This compound operates by binding to modulatory sites on GABA receptors, similar to traditional benzodiazepines. Deschloroetizolam is closely related to other substances such as etizolam (Etilaam), triazolam (Halcion), and alprazolam (Xanax). Since its emergence in the grey market of research chemicals in 2014, it has not been prescribed and is not classified as a controlled substance in many regions worldwide.

Pharmacological Properties

Deschloroetizolam exhibits a relatively rapid onset of action, providing symptomatic relief within 15 to 30 minutes of administration. It is considered to be half as potent as its parent compound, etizolam, yet has a duration of action that is approximately twice as long. The bioavailability and time to onset are comparable to those of etizolam. Notably, a dosage of 2 mg of deschloroetizolam is thought to be equivalent in potency to 10 mg of diazepam, highlighting its significant effects at lower doses.

Chemical Nomenclature and Class Membership

The systematic name for deschloroetizolam is 2-ethyl-9-methyl-4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine. It is classified as a depressant within the psychoactive class and falls under the chemical class of thienodiazepines. The compound's interaction with the benzodiazepine receptor site enhances the efficacy of the neurotransmitter gamma-aminobutyric acid (GABA), which is the primary inhibitory neurotransmitter in the brain. This modulation results in the calming and sedative effects associated with deschloroetizolam.

Dosage and Duration

The effects of deschloroetizolam can vary significantly based on dosage. The following dosage categories are commonly recognized:

• Threshold: 1 mg
• Light: 2 - 4 mg
• Common: 4 - 6 mg
• Strong: 6 - 12 mg
• Heavy: 12 mg and above

The total duration of effects typically ranges from 8 to 10 hours, with a peak effect occurring between 3 to 4 hours after administration. After effects may persist for an additional 3 to 6 hours.

Physical and Cognitive Effects

Deschloroetizolam produces a range of physical effects, including significant sedation, muscle relaxation, dizziness, and respiratory depression. Users often report an overwhelming sense of lethargy, particularly at higher doses, which can lead to a state of near-unconsciousness.

The cognitive effects of deschloroetizolam are multifaceted and tend to intensify with increased dosage. Users frequently describe a state of intense sedation accompanied by decreased inhibition. Prominent cognitive effects include:

• Amnesia
• Anxiety suppression
• Thought deceleration
• Analysis suppression
• Disinhibition
• Euphoria
• Compulsive redosing
• Emotion suppression
• Delusions of sobriety
• Dream potentiation

While deschloroetizolam primarily alleviates anxiety, it also dulls other emotions, albeit to a lesser extent than antipsychotic medications. Notably, users may experience delusions of sobriety, a phenomenon where individuals believe they are sober despite evident cognitive impairment.

Conclusion

Deschloroetizolam represents a significant addition to the thienodiazepine class, offering a unique profile of effects that may be beneficial for certain therapeutic applications. However, its potential for misuse and the lack of regulatory oversight necessitate caution among users and researchers alike. As with any psychoactive substance, understanding the pharmacological properties, potential effects, and risks associated with deschloroetizolam is crucial for informed use. Further research is warranted to explore its therapeutic potential, safety profile, and long-term effects on users.

Deschloroetizolam 5mg Pellets is for research use only and not intended for human consumption!

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Deschloroetizolam 5mg Pellets stock last updated at: April 2025